- Action Products, Inc. (Hagerstown)
- Advanced BioNutrition (Columbia)
- Advanced BioScience Laboratories, Inc. (Kensington)
- Athena Environmental Sciences Inc. (Baltimore)
- Atto Instruments, Inc. (Rockville)
- Brassica, Inc. (Baltimore)
- Becton Dickinson Microbiology Systems (Cockeysville)
- BioFactura (Rockville)
- Bioscience Contract Production Corporation (Baltimore)
- Biosys Inc. (Columbia)
- Biospherics, Inc. (Beltsville)Biotechnology Research Labs, Inc. (Rockville)
- Cell Trends, Inc. (Middletown)
- Chesapeake Biologicals (Baltimore)
- Chesapeake PERL (Savage)
- Chitin Works, Inc. (Cambridge)
- Claragen, Inc. (College Park)
- Crop Genetics International, Inc. (Columbia)
- Digene Corporation (Gaithersburg)
- EntreMed, Inc. (Rockville)
- Environmental Elements, Inc. (Baltimore)
- Gene Logic, Inc. (Rockville)
- Human Genome Sciences, Inc. (Rockville)
- Igen, Inc. (Rockville)
- Igene, Inc. (Columbia)
- Instrument Research Company, Inc. (Columbia)
- IOMAI (Gaithersburg)
- ISP Mineral Products, Inc. (Hagerstown)
- Kemp Biotechnologies, Inc. (Frederick)
- LifeTechnologies/BRL/Gibco, Inc. (Rockville)
- Magenta, Inc. (Baltimore)
- Marcor Media Development (Carlstadt, NJ)
- Martek Biosciences Corp. (Columbia)
- MedImmune, Inc. (Gaithersburg)
- Microbiological Associates (Rockville)
- Molecular Oncology, Inc. (Gaithersburg)
- New Earth Sciences, Inc. (Cambridge)
- Oceanix (Baltimore)
- Oncologix, Inc. (Rockville)
- OncoImmunin, Inc. (College Park)
- Oncor, Inc. (Gaithersburg)
- Paragon Biotech, Inc. (Baltimore)
- PerImmune, Inc.--now part of Intracel; (Frederick)
- Proneuron Co. (Rockville)
- Proteinix, Inc. (Rockville)
- SRCHEM, Inc. (Elkridge)
- Ventana Medical Systems (Gaithersburg)
- National Institutes of Health
- National Institute of Standards and Technology
- Naval Research Laboratory
- US Army, Edgewood Research Development and Engineering Center (ERDEC)
- US Army, Walter Reed Research Institute
- United States Department of Agriculture, Beltsville, MD, Martinsburg, WV